Avellino corneal dystrophy is an autosomal dominant genetic disorder characterized by abnormal protein deposits that accumulate in the central cornea. These deposits may form spontaneously or be triggered by corneal trauma or ultraviolet (UV) exposure.
In patients with Avellino corneal dystrophy, laser vision correction procedures such as LASIK or LASEK can accelerate disease progression and, in severe cases, result in significant and irreversible vision loss.
For this reason, comprehensive preoperative screening—including genetic testing and detailed corneal evaluation—is essential to identify this condition in advance and ensure safe, appropriate treatment decisions.